Recommendations for conducting the rodent erythrocyte Pig‐a assay: A report from the HESI GTTC Pig‐a Workgroup
نویسندگان
چکیده
منابع مشابه
The genotypic and phenotypic spectrum of PIGA deficiency
BACKGROUND Phosphatidylinositol glycan biosynthesis class A protein (PIGA) is one of the enzymes involved in the biosynthesis of glycosylphosphatidylinositol (GPI) anchor proteins, which function as enzymes, adhesion molecules, complement regulators and co-receptors in signal transduction pathways. Until recently, only somatic PIGA mutations had been reported in patients with paroxysmal nocturn...
متن کاملPIGA-Virt: An Advanced Distributed MAC Protection of Virtual Systems
Efficient Mandatory Access Control of Virtual Machines remains an open problem for protecting efficiently Cloud Systems. For example, the MAC protection must allow some information flows between two virtual machines while preventing other information flows between those two machines. For solving these problems, the virtual environment must guarantee an in-depth protection in order to control th...
متن کاملTSPO PIGA Ligands Promote Neurosteroidogenesis and Human Astrocyte Well-Being
The steroidogenic 18 kDa translocator protein (TSPO) is an emerging, attractive therapeutic tool for several pathological conditions of the nervous system. Here, 13 high affinity TSPO ligands belonging to our previously described N,N-dialkyl-2-phenylindol-3-ylglyoxylamide (PIGA) class were evaluated for their potential ability to affect the cellular Oxidative Metabolism Activity/Proliferation i...
متن کاملExtracorporeal treatment for thallium poisoning: recommendations from the EXTRIP Workgroup.
BACKGROUND The EXtracorporeal TReatments In Poisoning (EXTRIP) workgroup was formed to provide recommendations on the use of extracorporeal treatment (ECTR) in poisoning. To test and validate its methods, the workgroup reviewed data for thallium (Tl). METHODS After an extensive search, the co-chairs reviewed the articles, extracted the data, summarized findings, and proposed structured voting...
متن کاملExtracorporeal treatment for acetaminophen poisoning: recommendations from the EXTRIP workgroup.
BACKGROUND The Extracorporeal Treatments in Poisoning (EXTRIP) workgroup was created to provide evidence-based recommendations on the use of extracorporeal treatments (ECTR) in poisoning and the results are presented here for acetaminophen (APAP). METHODS After a systematic review of the literature, a subgroup selected and reviewed the articles and summarized clinical and toxicokinetic data i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Environmental and Molecular Mutagenesis
سال: 2021
ISSN: 0893-6692,1098-2280
DOI: 10.1002/em.22427